Format

Send to

Choose Destination
Science. 1991 Dec 13;254(5038):1627-30.

Molecular architecture and electrostatic properties of a bacterial porin.

Author information

1
Institut für Organische Chemie und Biochemie, Freiburg, Federal Republic of Germany.

Abstract

The integral membrane protein porin from Rhodobacter capsulatus consists of three tightly associated 16-stranded beta barrels that give rise to three distinct diffusion channels for small solutes through the outer membrane. The x-ray structure of this porin has revealed details of its shape, the residue distributions within the pore and at the membrane-facing surface, and the location of calcium sites. The electrostatic potential has been calculated and related to function. Moreover, potential calculations were found to predict the Ca2+ sites.

PMID:
1721242
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center