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Trends Endocrinol Metab. 2007 Mar;18(2):52-7. Epub 2007 Jan 5.

A new expression of diabetes: double diabetes.

Author information

1
Department of Endocrinology & Diabetes, Campus Bio-Medico University, Via E Longoni 83, 00155 Rome, Italy. p.pozzilli@unicampus.it

Abstract

Diabetes is on the increase worldwide. The incidence of both type 1 and type 2 diabetes has shown a rise, in parallel with a notable increase in the incidence of a new expression of the disease in children and adolescents, with the characteristics of a mixture of the two types of diabetes, and referred to as 'double diabetes'. Insulin resistance and obesity, together with the presence of markers of pancreatic autoimmunity - namely, autoantibodies to islet cell antigens - typically define this condition. However, recognition of double diabetes can pose problems. In most cases, a reduction in the 'autoimmune load' and an increase in the 'metabolic load' are helpful for attaining a correct diagnosis in a diabetic child.

PMID:
17208448
DOI:
10.1016/j.tem.2006.12.003
[Indexed for MEDLINE]

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