Curr Biol. 2007 Jan 9;17(1):R18-20.

Microtubule modification: acetylation speeds anterograde traffic flow.

Author information

1: Biological Sciences and Pathology & Cell Biology, Columbia University, 804A Sherman Fairchild Center, MC 2450, 1212 Amsterdam Avenue, New York, New York 10027-2450, USA. jcb4@columbia.edu

Abstract

Microtubules in neurites undergo multiple post-translational modifications. Recent work shows that neurites enriched in acetylated microtubules selectively support kinesin-mediated transport of the JNK regulator JIP-1 to growth cones.