sHLA-G expression: is it really worth measuring?

Reprod Biomed Online. 2007 Jan;14(1):9-10. doi: 10.1016/s1472-6483(10)60756-0.

Abstract

HLA-G is believed to play a pivotal role in the immunoprotection of the semiallogenic embryo. Its expression during pre- and early implantation is correlated with the cleavage rate of the embryo. Studies in congenic mice have revealed that mRNA of both the maternal and paternal haplotypes are present in zygotes and in embryos at all stages of development.

Publication types

  • Comment

MeSH terms

  • Adult
  • Animals
  • Embryo, Mammalian / immunology*
  • Embryo, Mammalian / metabolism
  • Female
  • HLA Antigens / biosynthesis*
  • HLA Antigens / genetics
  • HLA-G Antigens
  • Histocompatibility Antigens Class I / biosynthesis*
  • Histocompatibility Antigens Class I / genetics
  • Humans
  • Mice
  • Pregnancy
  • Pregnancy Rate
  • RNA, Messenger / metabolism

Substances

  • HLA Antigens
  • HLA-G Antigens
  • Histocompatibility Antigens Class I
  • RNA, Messenger