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Epilepsia. 2006 Dec;47(12):2086-91.

Psychiatric comorbidity in juvenile myoclonic epilepsy.

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Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.



To assess the prevalence of psychiatric disturbances among patients with juvenile myoclonic epilepsy (JME).


Forty-three patients with JME (22 female, 21 male, mean age 32.4+/-13, range 15-63) were assessed by means of the Structured Clinical Interviews for DSM-IV (SCID-I and SCID-II). Current and lifetime psychiatric diagnoses were assigned.


Thirty-five percent of the JME patients suffered from one or more psychiatric disorders (Axis I and Axis II). Personality disorders were present in 23% and Axis I disorders in 19%. Altogether, 47% had a psychiatric disorder at any time of their life.


Psychiatric diagnoses are slightly higher than in representative community samples. The substantially increased number of personality disorders in JME patients might be attributed to frontal lobe deficits.

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