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Cell. 2006 Dec 29;127(7):1306-7.

Retrograde control of neural circuit formation.

Author information

1
The Solomon H. Snyder Department of Neuroscience, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Abstract

Glial-derived neurotrophic factor (GDNF), secreted by skeletal muscle, triggers expression of the ETS transcription factor Pea3 in a subset of motor neurons in the spinal cord. In this issue, find that this retrograde GDNF-Pea3 signal controls dendrite patterning and assembly of a sensory-motor reflex circuit.

PMID:
17190596
DOI:
10.1016/j.cell.2006.12.013
[Indexed for MEDLINE]
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