Format

Send to

Choose Destination
See comment in PubMed Commons below
Acta Med Okayama. 2006 Dec;60(6):351-5.

Detection of fibronectin-binding proteins in Clostridium perfringens.

Author information

1
Department of Life Sciences, Okayama University of Science, Okayama 700-0005, Japan. katayama@dbc.ous.ac.jp

Abstract

Clostridium perfringens is an anaerobic spore-forming pathogen of humans and animals. C. perfringens type A strains, 13, CPN50, and NCTC8237, isolated from human gas gangrene, bound specifically to human fi bronectin (Fn). The trypsin-treatment of the bacterial cells significantly reduced the Fn-binding. A ligand blotting analysis of all three C. perfringens strains revealed that 5 protein bands of 34 kDa, 29 kDa, 26 kDa, 17 kDa, and 12 kDa specifically bound to biotinylated Fn. These results suggest that C. perfringens possesses certain Fn-binding proteins on the cell surface.

PMID:
17189979
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Okayama University Medical School
    Loading ...
    Support Center