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Mol Cell. 2006 Dec 28;24(6):807-8.

To die or not to die: a HAT trick.

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  • 1LBME, CNRS and Universit√© Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse, France.

Abstract

In this issue of Molecular Cell, two manuscripts (Sykes et al., 2006) propose that the decision to undergo apoptosis upon DNA damage is mediated through acetylation of p53 within its DNA-binding domain by MYST histone acetyltransferases.

PMID:
17189182
DOI:
10.1016/j.molcel.2006.12.005
[PubMed - indexed for MEDLINE]
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