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Curr Opin Cell Biol. 1991 Oct;3(5):800-4.

Anti-adhesive molecules of the extracellular matrix.

Author information

1
Friedrich Miescher Institute, Basel, Switzerland.

Abstract

The prototype extracellular matrix glycoproteins had been identified on the basis of their activity in promoting cell adhesion and spreading. Recently, more and more evidence is accumulating that the reverse effect of extracellular matrix proteins, namely the inhibition of cell adhesion and spreading, may be equally important for proper cell function during morphogenesis and development. Several anti-adhesive proteins have been described and their mechanisms of action are being investigated.

PMID:
1718339
DOI:
10.1016/0955-0674(91)90053-2
[Indexed for MEDLINE]

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