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Nat Rev Mol Cell Biol. 2007 Jan;8(1):85-90.

The chromatoid body: a germ-cell-specific RNA-processing centre.

Author information

1
Department of Physiology, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland.

Abstract

The chromatoid body, a unique cloud-like structure of male germ cells, moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades. Recent findings indicate that microRNA and RNA-decay pathways converge to the chromatoid body. This highly specialized structure might function as an intracellular focal domain that organizes and controls RNA processing in male germ cells.

PMID:
17183363
DOI:
10.1038/nrm2081
[Indexed for MEDLINE]
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