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Br J Cancer. 2007 Jan 15;96(1):1-5. Epub 2006 Dec 19.

The potential role of podoplanin in tumour invasion.

Author information

1
Department of Clinical-Biological Sciences, Institute of Biochemistry and Genetics, Centre for Biomedicine, University of Basel, Basel, Switzerland.

Abstract

Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.

PMID:
17179989
PMCID:
PMC2360213
DOI:
10.1038/sj.bjc.6603518
[Indexed for MEDLINE]
Free PMC Article

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