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Clin Rheumatol. 2007 Aug;26(8):1275-7. Epub 2006 Dec 15.

Clinical features of scleroderma patients with contracture of phalanges.

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1
Department of Dermatology, Faculty of Medicine, University of Tokyo, and Mita Hospital, Tokyo, Japan.

Abstract

Contracture of phalanges (CP) is a frequent complication of patients with systemic sclerosis (SSc). The objective of this study was to examine the prevalance of CP in patients with SSc and investigate the clinical and laboratory features of SSc patients with CP. Three hundred and fifty patients with SSc were examined. CP was found in 164 of the 350 patients (47%) with SSc. The prevalence of oesophageal involvement, pulmonary fibrosis or heart involvement was significantly greater in the patients with CP than that in those without CP. Our study suggested that the presence of CP may be a marker of oesophageal involvement, pulmonary fibrosis and heart involvement.

PMID:
17171315
DOI:
10.1007/s10067-006-0490-0
[Indexed for MEDLINE]
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