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FEMS Microbiol Rev. 2007 Jan;31(1):101-7. Epub 2006 Dec 1.

Vaccination against meningococcal disease in Europe: review and recommendations for the use of conjugate vaccines.

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Immunization Department, Health Protection Agency Centre for Infections, London, UK.


At the end of 2005, six European countries had implemented public immunization campaigns with serogroup C conjugate vaccines, and all had experienced substantial declines in the incidence of serogroup C disease. A quadrivalent ACWY meningococcal vaccine is in use in the USA, but serogroup A is extremely rare in Europe and serogroups Y and W135 are infrequent causes of disease. This paper outlines recommendations on the use of conjugate vaccines in Europe based on the experience with meningococcal C conjugate (MCC) vaccines so far.

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