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ACS Chem Biol. 2006 Nov 21;1(10):615-8.

Regulation and specificity of S-nitrosylation and denitrosylation.

Author information

1
Division of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. srt@mit.edu

Abstract

Signal transduction from nitric oxide (NO) is important in physiological processes such as smooth muscle relaxation and neurotransmission. NO signaling occurs through a variety of mechanisms, including S-nitrosylation (SNO) of sulfhydryl groups in protein. A paper in this issue of the journal dissects the regulatory system involved in SNO of caspase-3 and highlights the need for more direct investigations of the complex biological regulation by NO signaling.

PMID:
17168564
DOI:
10.1021/cb600439h
[Indexed for MEDLINE]

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