Send to

Choose Destination
ACS Chem Biol. 2006 May 23;1(4):207-10.

Act globally, think locally: systems biology addresses the PDZ domain.

Author information

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

Erratum in

  • ACS Chem Biol. 2010 Jul 16;5(7):713.


Interaction networks, cartography and mapping, wiring and circuitry, whichever metaphor is invoked, the cardinal questions regarding cellular proteins are the same: What are they? How much is there? What do they do, and to whom do they do it? One of the more recent proteomics tools to pursue these lines of inquiry is the protein microarray, and a current report has unleashed this formidable technique upon a target of considerable biological interest, the PDZ domain family of signaling molecules.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center