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Structure. 2006 Dec;14(12):1731-40.

Oligomeric structure, dynamics, and orientation of membrane proteins from solid-state NMR.

Author information

1
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA. mhong@iastate.edu <mhong@iastate.edu>

Abstract

Solid-state NMR is a versatile and powerful tool for determining the dynamic structure of membrane proteins at atomic resolution. I review the recent progress in determining the orientation, the internal and global protein dynamics, the oligomeric structure, and the ligand-bound structure of membrane proteins with both alpha-helical and beta sheet conformations. Examples are given that illustrate the insights into protein function that can be gained from the NMR structural information.

PMID:
17161364
DOI:
10.1016/j.str.2006.10.002
[Indexed for MEDLINE]
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