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J Neurol Neurosurg Psychiatry. 2007 Apr;78(4):399-402. Epub 2006 Nov 30.

Blood pressure in head-injured patients.

Author information

1
Department of Neurosurgery, Newcastle General Hospital, Newcastle upon Tyne, UK.

Abstract

OBJECTIVE:

To determine the statistical characteristics of blood pressure (BP) readings from a large number of head-injured patients.

METHODS:

The BrainIT group has collected high time-resolution physiological and clinical data from head-injured patients who require intracranial pressure (ICP) monitoring. The statistical features of this dataset of BP measurements with time resolution of 1 min from 200 patients is examined. The distributions of BP measurements and their relationship with simultaneous ICP measurements are described.

RESULTS:

The distributions of mean, systolic and diastolic readings are close to normal with modest skewing towards higher values. There is a trend towards an increase in blood pressure with advancing age, but this is not significant. Simultaneous blood pressure and ICP values suggest a triphasic relationship with a BP rising at 0.28 mm Hg/mm Hg of ICP, for ICP up to 32 mm Hg, and 0.9 mm Hg/mm Hg of ICP for ICP from 33 to 55 mm Hg, and falling sharply with rising ICP for ICP >55 mm Hg.

CONCLUSIONS:

Patients with head injury appear to have a near normal distribution of blood pressure readings that are skewed towards higher values. The relationship between BP and ICP may be triphasic.

PMID:
17138594
PMCID:
PMC2077799
DOI:
10.1136/jnnp.2006.100172
[Indexed for MEDLINE]
Free PMC Article

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