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Transpl Immunol. 2006 Nov;16(3-4):250-3. Epub 2006 Sep 7.

Late onset of severe graft-versus-host disease following liver transplantation.

Author information

  • 1National Institute of Living Donor Liver Transplantation, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu 210029, P.R. China. sunbc@njmu.edu.cn

Abstract

Graft versus host disease (GVHD) is an uncommon but lethal complication following liver transplantation that results from the engraftment of T lymphocytes associated with the liver graft. It usually occurs 2 to 6 weeks after the procedure. We herein report a case of late onset of severe GVHD 4 months after cadaveric liver transplantation for hepatocellular carcinoma in a 54-year-old woman, which was characterized by refractory diarrhea and abdominal pain. Moreover we discuss risk factors of GVHD including the recipient age and cytomegalovirus (CMV) infection.

PMID:
17138062
DOI:
10.1016/j.trim.2006.08.006
[PubMed - indexed for MEDLINE]
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