Format

Send to

Choose Destination
Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2546-8. Epub 2006 Nov 28.

Prolonged prevention of squamous cell carcinoma of the skin by regular sunscreen use.

Author information

1
School of Population Health, University of Queensland, Brisbane, Queensland 4029, Australia.

Abstract

Half of all cancers in the United States are skin cancers. We have previously shown in a 4.5-year randomized controlled trial in an Australian community that squamous cell carcinomas (SCC) but not basal cell carcinomas (BCC) can be prevented by regular sunscreen application to the head, neck, hands, and forearms. Since cessation of the trial, we have followed participants for a further 8 years to evaluate possible latency of preventive effect on BCCs and SCCs. After prolonged follow-up, BCC tumor rates tended to decrease but not significantly in people formerly randomized to daily sunscreen use compared with those not applying sunscreen daily. By contrast, corresponding SCC tumor rates were significantly decreased by almost 40% during the entire follow-up period (rate ratio, 0.62; 95% confidence interval, 0.38-0.99). Regular application of sunscreen has prolonged preventive effects on SCC but with no clear benefit in reducing BCC.

PMID:
17132769
DOI:
10.1158/1055-9965.EPI-06-0352
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center