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Nutr Rev. 2006 Nov;64(11):502-7.

Effects of intended weight loss on morbidity and mortality: possible explanations of controversial results.

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Institute for Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark.


Long-term, population-based, observational studies have shown that intended weight loss does not always reduce the mortality associated with obesity. The effects of weight loss on mortality may be a balance between the effects of the loss of harmful abdominal and ectopic fat mass and the loss of beneficial peripheral subcutaneous fat mass and lean body mass.

[Indexed for MEDLINE]

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