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Immunol Today. 1991 Mar;12(3):A7-12.

The acute phase protein response during parasitic infection.

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Dept of Pediatrics, IWK Children's Hospital, Dalhousie University, Halifax, Canada.


There is a paucity of comprehensive studies of the APP response in parasitic infection. This should be remedied for two reasons. First, as there is a limited number of cytokines with hepatocyte-stimulating activities, and as each one elicits a unique spectrum of protein changes, examination of the APP response during infection could provide insight into the cytokines involved. Second, the presence of IL-1, IL-6 and TNF, the mediators of the APR, in tissues and circulation have important implications for subsequent immune responses.

[Indexed for MEDLINE]

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