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Clin Biochem. 2007 Jan;40(1-2):141-2. Epub 2006 Oct 19.

Regular exercise attenuated lipid peroxidation in adolescents with Down's syndrome.

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  • 1Sport Medicine School, Virgen del Saliente s/n, 11100 San Fernando, Cádiz, Spain.

Abstract

OBJECTIVES:

This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome.

MATERIALS AND METHODS:

Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax=194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC).

RESULTS:

When compared to baseline, MDA content was decreased significantly.

CONCLUSION:

Regular exercise significantly decreased lipoperoxidation in Down's syndrome.

[PubMed - indexed for MEDLINE]
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