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Can J Psychiatry. 2006 Oct;51(11):711-4.

One-year stability of diagnosis in first-episode nonaffective psychosis: influence of sex.

Author information

1
Department of Psychiatry, University of Toronto, Ontario.

Abstract

OBJECTIVE:

To determine whether sex influences the frequency and direction of diagnostic change 1 year after a first episode of nonaffective psychosis.

METHOD:

The subjects (n = 228) were individuals diagnosed with schizophrenia and other psychoses according to DSM-IV criteria at baseline and at 1 year.

RESULTS:

When diagnostic shifts occurred, men mainly shifted toward schizophrenia (84.6%), which was associated with more severe symptoms. In contrast, 72% of women in whom a diagnostic shift occurred shifted away from a schizophrenia spectrum disorder toward mood disorder. A shift to mood disorder in women was associated with an early age of illness onset.

CONCLUSIONS:

At initial presentation, nonaffective first-episode psychosis studies may underestimate the number of men and overestimate the number of women who will eventually receive a schizophrenia diagnosis.

PMID:
17121170
DOI:
10.1177/070674370605101108
[Indexed for MEDLINE]

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