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Immunol Today. 1991 Apr;12(4):124-9.

Antigen presentation: structural themes and functional variations.

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1
Dept. of Pathology, Washington University School of Medicine, St. Louis, MO 63110.

Abstract

T cells recognize nonnative processed fragments of antigens presented in association with major histocompatibility complex (MHC) class I or class II molecules. Recently, an accumulating body of evidence has provided a functional linkage between antigen presentation events and the cell biology of MHC molecule assembly and transport. In this review Thomas and Vivian Braciale synthesize these developments into a cohesive model of MHC assembly and antigen presentation pathways.

PMID:
1711855
DOI:
10.1016/0167-5699(91)90096-C
[Indexed for MEDLINE]
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