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Breast Cancer Res. 2006;8(6):112.

Intrauterine exposures, pregnancy estrogens and breast cancer risk: where do we currently stand?

Author information

1
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 M, Asias Street, Goudi, GR-115 27, Athens, Greece. pdlagiou@med.uoa.gr

Abstract

Since 1990, when a hypothesis on intrauterine influences on breast cancer risk was published, several studies have provided supportive, indirect evidence by documenting associations of birth weight and other correlates of the prenatal environment with breast cancer risk in offspring. Recent results from a unique cohort of women with documented exposure to diethylstilbestrol in utero have provided direct evidence in support of a potential role of pregnancy oestrogens on breast cancer risk in offspring.

PMID:
17118219
PMCID:
PMC1797035
DOI:
10.1186/bcr1615
[Indexed for MEDLINE]
Free PMC Article
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