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Eur J Med Chem. 2007 Feb;42(2):125-37. Epub 2006 Nov 15.

A review of anti-infective and anti-inflammatory chalcones.

Author information

1
Department of Chemistry, Adam Mickiewicz University, Grunwaldzka, PoznaƄ, Poland. zdzisian@amu.edu.pl <zdzisian@amu.edu.pl>

Abstract

Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. The purpose of this review is to provide an overview of the pharmacological activity of synthetic and naturally occurring chalcones. This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.

PMID:
17112640
DOI:
10.1016/j.ejmech.2006.09.019
[Indexed for MEDLINE]

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