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Nat Immunol. 2006 Dec;7(12):1277-9.

From antigen processing to peptide-MHC binding.

Author information

1
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. unanue@pathbox.wustl.edu

Abstract

Emil R. Unanue recounts his seminal work 25 years ago demonstrating that antigens are phagocytosed and processed by antigen-presenting cells and that class II major histocompatibility complex molecules are peptide-binding proteins.

PMID:
17110945
DOI:
10.1038/ni1206-1277
[Indexed for MEDLINE]

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