Format

Send to

Choose Destination
Clin Vaccine Immunol. 2007 Jan;14(1):110-3. Epub 2006 Nov 8.

Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis.

Author information

1
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. narisara@tropmedres.ac

Abstract

Five enzyme-linked immunosorbent assays developed to detect antibodies to different Burkholderia pseudomallei antigen preparations were evaluated as diagnostic tests for melioidosis in northeast Thailand. The highest diagnostic indices were observed for an affinity-purified antigen (sensitivity, 82%; specificity, 72%) and crude B. pseudomallei antigen (sensitivity, 81%; specificity, 70%), an improvement over the indirect hemagglutination assay (sensitivity, 73%; specificity, 64%).

PMID:
17093104
PMCID:
PMC1797717
DOI:
10.1128/CVI.00289-06
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center