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Free Radic Res. 2006 Dec;40(12):1335-8.

Lipofuscin-like fluorophores originated from malondialdehyde.

Author information

1
Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan. uchidak@agr.nagoya-u.ac.jp

Abstract

The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of post-mitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and lipid. In the present mini-review, I provide a comprehensive summary of fluorescent adducts originated from malondialdehyde (MDA).

PMID:
17090422
DOI:
10.1080/10715760600902302
[Indexed for MEDLINE]

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