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Biochem Biophys Res Commun. 1991 Mar 29;175(3):1125-30.

Cloning and sequencing of human FSH receptor cDNA.

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  • 1Department of Obstetrics and Gynecology, Gunma University School of Medicine, Japan.

Erratum in

  • Biochem Biophys Res Commun 1994 Jun 15;201(2):1057.


We have isolated and sequenced a cDNA encoding the follicle stimulating hormone (FSH) receptor. The deduced amino acid sequence (678 residues) containing seven putative transmembrane segments which displays sequence similarity to G protein-coupled receptors. The receptor consists of 359 residue extracellular domain which contains four N-linked glycosylation sites. While the protein is 89% identical overall with the previously cloned rat FSH receptor, the most highly conserved regions are the putative transmembrane segments (95% similarity).

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