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Curr Opin Neurobiol. 2006 Dec;16(6):638-44. Epub 2006 Nov 3.

Mechanisms for recovery of motor function following cortical damage.

Author information

1
University of Kansas Medical Center, Landon Center on Aging, MS 1005 3901 Rainbow Boulevard, Kansas City, KS 66160, USA. rnudo@kumc.edu

Abstract

Recent studies of focal injury to the cerebral cortex have demonstrated that the remaining, intact tissue undergoes structural and functional changes that could play a substantial role in neurological recovery. New information regarding the molecular and cellular environment in the adjacent, intact tissue has suggested that waves of growth promotion and inhibition modulate the self-repair processes of the brain. Furthermore, recent studies have documented widespread neurophysiological and neuroanatomical changes in regions remote from a focal cortical injury, suggesting that entire cortical networks participate in the recovery process.

PMID:
17084614
DOI:
10.1016/j.conb.2006.10.004
[Indexed for MEDLINE]

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