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Nat Rev Drug Discov. 2006 Nov;5(11):919-31.

The obesity pipeline: current strategies in the development of anti-obesity drugs.

Author information

1
Thiakis Limited, Imperial BioIncubator, Bessemer Building (RSM), Prince Consort Road, London SW7 2BP, UK.

Abstract

This review provides a summary of currently available pharmaceutical therapies for the treatment of obesity, along with an overview of the pipeline of products currently in development, and the key mechanisms on which the major development candidates are based. In particular, the recent increase in understanding of the role of gut peptides in energy homeostasis is highlighted as a promising source of potential future obesity therapies.

PMID:
17080028
DOI:
10.1038/nrd2136
[Indexed for MEDLINE]
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