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Curr Neurol Neurosci Rep. 2006 Nov;6(6):477-80.

Posterior cortical atrophy: a brief review.

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  • 1Department of Neurology, Vanderbilt University School of Medicine, 2311 Pierce Avenue, Nashville, TN 37232-3375, USA.


Posterior cortical atrophy is a striking clinical syndrome in which a dementing illness begins with visual symptoms. Initially, the problem may seem to be loss of elementary vision, but over time the patient develops features of visual agnosia, topographical difficulty, optic ataxia, simultanagnosia, ocular apraxia (Balint's syndrome), alexia, acalculia, right-left confusion, and agraphia (Gerstmann's syndrome), and later a more generalized dementia. Occasional patients have visual hallucinations and signs of Parkinson's disease or Lewy body dementia. A number of different neuropathologic disorders are associated with posterior cortical atrophy.

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