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Brain Res. 1990 Aug 27;526(1):127-34.

In vivo anterograde and retrograde axonal transport of the fluorescent rhodamine-dextran-amine, Fluoro-Ruby, within the CNS.

Author information

1
Department of Otolaryngology, University of Virginia, Charlottesville 22908.

Abstract

A number of fluorescent dextrans were screened for axonal transport properties within the rat CNS. One compound, Fluoro-Ruby (FR), was found to be particularly sensitive for demonstrating retrograde and particularly anterograde axonal transport. The tracer may be either pressure or iontophoretically injected, and the fixed tissue can be examined without histochemical processing. The technique can be combined with a wide variety of other neuroanatomical methods.

PMID:
1706635
DOI:
10.1016/0006-8993(90)90258-d
[Indexed for MEDLINE]

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