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Am J Ophthalmol. 2007 Jan;143(1):23-31. Epub 2006 Sep 1.

Surgical complications in the Tube Versus Trabeculectomy Study during the first year of follow-up.

Author information

1
Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW 17th Street, Miami, FL 33136, USA. sgedde@med.miami.edu

Abstract

PURPOSE:

To describe the intraoperative and postoperative complications encountered during the first year of follow-up in the Tube Versus Trabeculectomy (TVT) Study.

DESIGN:

Multicenter randomized clinical trial.

METHODS:

SETTING:

Seventeen clinical centers.

STUDY POPULATION:

Two hundred twelve patients aged 18 to 85 years who had undergone previous trabeculectomy and/or cataract extraction with intraocular lens implantation and uncontrolled glaucoma with intraocular pressure > or =18 mm Hg and < or =40 mm Hg on maximum tolerated medical therapy.

INTERVENTIONS:

A 350-mm(2) Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC).

MAIN OUTCOME MEASURES:

Surgical complications, reoperation for complications, visual acuity, and cataract progression.

RESULTS:

Intraoperative complications occurred in seven patients (7%) in the tube group and 10 patients (10%) in the trabeculectomy group (P = .59). Postoperative complications developed in 36 patients (34%) in the tube group and 60 patients (57%) in the trabeculectomy group during the first year of follow-up (P = .001). Surgical complications were associated with reoperation and/or loss of > or =2 lines of Snellen visual acuity in 18 patients (17%) in the tube group and 28 patients (27%) in the trabeculectomy group (P = .12).

CONCLUSIONS:

There were a large number of surgical complications during the first year of follow-up in the study, but most were self-limited. The incidence of postoperative complications was higher after trabeculectomy with MMC than nonvalved tube shunt surgery. Serious complications resulting in reoperation and/or vision loss occurred with similar frequency with both surgical procedures.

PMID:
17054896
DOI:
10.1016/j.ajo.2006.07.022
[Indexed for MEDLINE]

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