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Biochem Soc Trans. 2006 Nov;34(Pt 5):671-4.

The role of myosin Va in secretory granule trafficking and exocytosis.

Author information

1
Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway.

Abstract

It emerges that myosin Va plays multiple roles in the trafficking of SGs (secretory granules). In addition to a function in the capture and transport of newly formed SGs in the F-actin-rich cortex, myosin Va is implicated in late transport events of these organelles, which precede their exocytosis. Consistent with these roles, interactions of myosin Va with an array of well-known proteins involved in regulated protein secretion have been documented.

PMID:
17052171
DOI:
10.1042/BST0340671
[Indexed for MEDLINE]

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