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Planta Med. 2006 Dec;72(15):1421-4. Epub 2006 Oct 18.

Action of (2-->1)Fructo-oligopolysaccharide fraction of Chlorophytum borivilianum against Streptozotocin-Induced oxidative stress.

Author information

1
Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow, India. narasimhansreevidyan@rediffmail.com

Abstract

A fructo-oligosaccharide was isolated from Chlorophytum borivilianum and identified as O-beta-D-fructofuranosyl-(2-->1)-(beta-D-fructofuranosyl) (n)-(2-->1)-alpha-D-glucopyranoside (n = 5 - 30) using high-pressure anion exchange chromatography, MALDI-MS, NMR, GC, HPTLC and chemical analysis. The extract and the fructo-oligosaccharide were found to have significant antidiabetic activity with the blood sugar levels being 118.32 +/- 3.56 and 110.21 +/- 4.22, respectively, as compared to the control value of 231.25 +/- 3.03 along with moderate antioxidant activity in streptozotocin-induced diabetic animals.

PMID:
17051465
DOI:
10.1055/s-2006-951705
[Indexed for MEDLINE]

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