Format

Send to

Choose Destination
See comment in PubMed Commons below
Zhongguo Zhong Yao Za Zhi. 2006 Aug;31(15):1225-6, 1260.

[Review about mechanisms of anti-cancer of Solanum nigrum].

[Article in Chinese]

Author information

1
Institute of Medicinal Plant Devlopment, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Abstract

This paper gave a brief introduction of the effect of Solanum nigrum on anti-cancer. The experimental results showed that the total alkaloid isolated from S. nigrum interfered structure and function of tumor cell membrane, disturbed the synthesis of DNA and RNA, changed the cell cycle distribution, so that total alkaloids could play in inhibabition to tumor cells, while the glycoprotein (150 x 10(3)) isolated from S. nigrum might have shown anti-cancer abilities by blocking the anti-apoptotic pathway of NF-kappaB, activating caspase cascades reaction and increasing the production of nitric oxide.

PMID:
17048560
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center