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J Clin Rheumatol. 2004 Aug;10(4):210-3.

Polyarteritis nodosa complicated by catastrophic antiphospholipid syndrome.

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From the *Rheumatic Diseases Division and the †Department of Internal Medicine, University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas.


Polyarteritis nodosa (PAN) is a vasculitis of small- and medium-sized vessels, characterized by vascular aneurysms that can lead to ischemia and infarction. We present the case of a patient with classic polyarteritis nodosa in abdominal organs who additionally demonstrated antitreponemal and antiphospholipid antibodies, resulting in a severe cerebral thrombosis. This case highlights: 1. The potential for false-positive syphilis serology in PAN patients, and 2. The rare coexistence of polyarteritis nodosa and the catastrophic antiphospholipid syndrome.

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