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J Bacteriol. 2006 Dec;188(24):8662-5. Epub 2006 Oct 13.

BadM is a transcriptional repressor and one of three regulators that control benzoyl coenzyme A reductase gene expression in Rhodopseudomonas palustris.

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1
Department of Microbiology, Box 357242, 1959 N. E. Pacific Street, University of Washington, Seattle, WA 98195-7242, USA.

Abstract

The rate-limiting enzyme of anaerobic benzoate degradation by Rhodopseudomonas palustris, benzoyl coenzyme A (CoA) reductase, is highly sensitive to oxygen, and its synthesis is tightly regulated. We determined that a previously unknown gene in the benzoate gene cluster, badM, encodes a transcriptional repressor of benzoyl-CoA reductase gene expression. BadM controls gene expression from the benzoyl-CoA reductase promoter in concert with two previously described transcriptional activators.

PMID:
17041049
PMCID:
PMC1698244
DOI:
10.1128/JB.01312-06
[Indexed for MEDLINE]
Free PMC Article
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