Objective: To optimize the conditions for the extraction of panax notogingseng saponins (PNS).
Methods: After selected extraction solvent and suitable particle, we employed orthogonal experimental design to examine the conditions for the extraction by determination of PNS.
Results: Significant effect was observed only in extraction times.
Conclusion: The optimum condition for extraction of PNS was to extract panax notogingseng (Burk.) F. H. Chen with 10 times 70% ethanol for 1.5 hours for 3 times.