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Curr Opin Infect Dis. 1998 Jun;11(3):271-8.

Fc receptor and complement receptor-mediated phagocytosis in host defence.

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Department of Immunology, University Hospital Utrecht, Utrecht, The Netherlands.


In the past few years significant progress in the area of phagocyte biology has been made in unravelling the mechanism of phagocytosis. In this review we discuss the characteristics and functions of complement and Fc receptors and the role they play as bridges between humoral and cellular immunity. We focus on the function of these receptors in a comprehensive way and propose a novel model to explain the integration of various signals for the optimal functioning of phagocytic cells.


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