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West Afr J Med. 1990 Jan-Mar;9(1):44-9.

Tamoxifen in the management of advanced breast carcinoma in Nigerian women.

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Department of Surgery, University College Hospital, Ibadan, Nigeria.


Twenty-nine Nigerian women with advanced breast carcinoma treated with Tamoxifen (Nolvadex ICI) at a dosage of 20 mg twice daily have been reviewed. Eight of 26 evaluable patients had objective response (31%). No statistically significant association was found between response rate and menopausal status, previous chemotherapy or disease free interval. The drug was well tolerated with a low incidence of side effects. This study suggests that Tamoxifen is a useful drug in the adjuvant management of patients with advanced breast carcinoma in Nigeria.

[Indexed for MEDLINE]

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