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Curr Biol. 2006 Oct 10;16(19):R849-51.

Transcription: adjusting to adversity by regulating RNA polymerase.

Author information

1
Division of Biological Sciences and Center for Molecular Genetics, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0634, USA. epg@biomail.ucsd.edu

Abstract

Under growth-limiting conditions, budding yeast shut down transcription of genes of the translation apparatus. Recent studies have shown that this response is signaled, in part, by multiple pathways that converge on Maf1, leading to a change of this protein's phosphorylation state and its relocation to the nucleus, where it represses RNA polymerase III.

PMID:
17027482
DOI:
10.1016/j.cub.2006.08.071
[Indexed for MEDLINE]
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