Format

Send to

Choose Destination
See comment in PubMed Commons below
Phys Rev Lett. 2006 Sep 29;97(13):138102. Epub 2006 Sep 28.

Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection.

Author information

1
G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Abstract

Light scattered from biological tissues can exhibit an inverse power law spectral component. We develop a model based on the Born approximation and von Karman (self-affine) spatial correlation of submicron tissue refractive index to account for this. The model is applied to light scattering spectra obtained from excised esophagi of normal and carcinogen-treated rats. Power law exponents used to fit dysplastic tissue site spectra are significantly smaller than those from normal sites, indicating that changes in tissue self-affinity can serve as a potential biomarker for precancer.

PMID:
17026078
DOI:
10.1103/PhysRevLett.97.138102
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Physical Society
    Loading ...
    Support Center