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Curr Med Res Opin. 2006 Oct;22(10):2007-21.

Exogenous endoscopy-related infections, pseudo-infections, and toxic reactions: clinical and economic burden.

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1
College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA. pharmacoeconomics@osu.edu

Abstract

OBJECTIVES:

The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US.

METHODS:

A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based on a prospective protocol developed by the authors.

RESULTS:

The literature review included 70 outbreaks described in 64 scientific articles. Bronchoscopy accounted for half of all reported outbreaks. Inadequate decontamination practices were the leading cause of contamination; equipment malfunction became the second leading cause of contamination during the period 1990-2004. More than 91% of the infections identified could be prevented by health care providers if quality control systems are improved and implemented. The available economic information concerning exogenous endoscope related events is very limited. A model for the analysis of the economic burden of exogenous endoscopy-related events is proposed.

CONCLUSIONS:

Proper decontamination practices, the use of protective sheaths, and the improvement of surveillance systems could reduce the clinical and economic burdens associated with exogenous endoscopy-related events.

PMID:
17022860
DOI:
10.1185/030079906X121048
[Indexed for MEDLINE]

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