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Pediatr Dermatol. 2006 Sep-Oct;23(5):476-80.

Hypopituitarism in PHACES Association.

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Harvard Medical School, Boston, Massachusetts, USA.


The association consisting of posterior fossal malformations, cervicofacial, hemangiomas, arterial anomalies, cardiac defects, eye anomalies, and sternal clefting, or supraumbilical raphe, refers to the occurrence of congenital structural and vascular anomalies in the presence of a facial hemangioma. We report a patient with this association, growth retardation, and developmental delay who was found to have a partially empty sella turcica, central hypothyroidism, and growth hormone deficiency. Endocrinologic evaluation should be considered in any infant with this association.

[Indexed for MEDLINE]

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