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Curr Opin Anaesthesiol. 1998 Oct;11(5):485-96.

Neuroprotection (including hypothermia).

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Department of Anaesthesiology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

Erratum in

  • Curr Opin Anaesthesiol. 1999 Feb;12(1):110.


There have been over 2000 publications in the last year addressing the topic of neuroprotection. Novel and emerging therapeutic targets that have been explored include cerebral inflammation, hypothermia, neural transplantation and repair and gene therapy. Unfortunately, with few exceptions, the successes of experimental neuroprotection have not been translated into clinical practice. The possible reasons for the discrepancy between experimental success and clinical benefit are explored.


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