Abstract
Iron deprivation in bacteria causes the derepression of genes controlled by the ferric uptake regulator (Fur). The present microarray analysis of iron-starved Bacillus subtilis cells grown in minimal medium unveils additional physiological effects on a large number of genes linked to stringent-response regulation and to genes involved in amino acid biosynthesis associated with pathways essential for bacillibactin production.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acids / biosynthesis*
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Bacillus subtilis / growth & development*
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Bacillus subtilis / metabolism
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Bacillus subtilis / physiology
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Culture Media
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Esters
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Gene Expression Regulation, Bacterial*
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Iron / metabolism
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Oligonucleotide Array Sequence Analysis
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Oligopeptides / biosynthesis*
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Proteome
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Repressor Proteins / genetics
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Repressor Proteins / metabolism
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Transcription, Genetic
Substances
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Amino Acids
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Bacterial Proteins
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Culture Media
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Esters
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Oligopeptides
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Proteome
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Repressor Proteins
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bacillibactin
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ferric uptake regulating proteins, bacterial
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Iron