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Endocrinology. 1990 Dec;127(6):2665-72.

Expression of rat prolactin-like protein B in deciduoma of pseudopregnant rat and in decidua during early pregnancy.

Author information

1
Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

Abstract

The rat PRL-like protein-B (rPLP-B) complementary DNA (cDNA), originally cloned from a late term placental library, hybridizes to transcripts in the deciduoma tissue artificially produced in pseudopregnant rats. The expression of rPLP-B in deciduoma is first observed 48 h (pseudopregnancy day 7) after the deciduogenic stimulus and increases to a maximum by 96-120 h (pseudopregnancy day 9-10). In situ hybridization studies show that rPLP-B hybridizes specifically to the antimesometrial cells of deciduoma tissue in day 9 pseudopregnant rats and to the homologous cells of the decidua that surround the embryo-trophoblastic structure at day 9 of pregnancy. A temporal study on the expression of rPLP-B during pregnancy shows that rPLP-B is concomitantly expressed by the decidual cells of maternal origin and the cytotrophoblast of fetal origin around day 13 of pregnancy.

PMID:
1701123
DOI:
10.1210/endo-127-6-2665
[Indexed for MEDLINE]

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